Proteomics Research Blog

Please find below selected patents and scientific publications on our antibody microarray platform or its application in biomedical studies published in peer-reviewed journals. The articles were either published by our collaborators or customers or by Sciomics team. You will also find information on presentations at scientific conferences. 

Selected Scientific Publications by our Customers and Partners

2026

• Barmpa, K., Saraiva, C., Schwamborn, J. C. et al. (2026)
  Parkinson’s Disease Patient-Specific Striatum Organoids Show Hallmarks of Increased Inflammation. Mov Disord. (2026), published online February 11, 2026
• Luther, J., Carreau, A., Schinke, T. et al. (2026)
  Fos-induced osteosarcoma growth causes a cachexia-like phenotype in mice and correlates with high Fgf21 serum levels. Cancer Metab. (2026)

2025

• Mutschler, C.H., Seybold, B., Fiedler-Kalenka, M.O. et al. (2025)
  Optimizing Positive End-Expiratory Pressure in Asymmetric Acute Lung Injury in a Porcine Model: The Role of Transpulmonary Pressure. Int. J. Mol. Sci. 2025, 26(20), 9985.
• Yamada, S., Holomkova, K., Mustafa, K. et al. (2025)
  Long-Term Biobanked Dental Pulp Stem Cells Reatin Angiogenic Potential for Vascularised Tissue Engineering—Laboratory Investigation. Int Endod J. 2025; (online ahead of print).
• Melchers, S., Tengler, L., Nicolay, J.P. et al. (2025)
  Extracorporeal photopheresis therapy rapidly changes the cytokine profile and tumor microenvironment in cutaneous T cell lymphoma. Front Immunol. 2025;16:1669015.
• Matavelli, G., Helal, M., Riedel, A. et al. (2025)
  A TLR4-dependent fibroblast-monocyte axis in tumor-draining lymph nodes contributes to metastasis in triple-negative breast cancer. Immunity. 2025 Sep 15: S1074-7613(25)00378-4. 
• Certo, M., Pontarini, E., Mauro, C. et al. (2025)
  Lactate signalling leads to aggregation of immune-inflammatory hotspots and SLC5A12 blockade promotes their resolution. Nat Metab. 2025;7(8):1663-1680. 
• Zaradzki, M., Rehberg, F., Wagner, A.H. et al. (2025)
  Stabilisation of extracellular matrix is crucial to rapamycin-mediated life span increase in Marfan mgR/mgR mice. Biochem Pharmacol. 2025;235:116830

2024

• Kenzelmann, A., Boch, C., Schmidt, R., Richter, M., Schulz, M. (2024)
  Exploration of Novel Biomarkers for Neurodegenerative Diseases Using Proteomic Analysis and Ligand-Binding Assays. Biomedicines. 2024;12(12):2794 
• Lieder, H. R., Paket, U., Skyschally, A., Rink, A. D., Baars, T., Neuhäuser, M., Kleinbongard, P., Heusch, G.. (2024)
  Vago-splenic signal transduction of cardioprotection in humans. Eur Heart J. 2024;45(34):3164-3177.
• Michel, M., Renaud, D., Schmidt, R., Einkemmer, M., Laser, L.V., Michel, E., Dubowy, K.O., Karall, D., Laser, K.T., Scholl-Bürgi, S. (2024)
  Altered Serum Proteins Suggest Inflammation, Fibrogenesis and Angiogenesis in Adult Patients with a Fontan Circulation. Int. J. Mol. Sci. 25, 5416.
• Ringelhan, M., Schuehle, S., van de Klundert, M., Kotsiliti, E., Plissonnier, M.-L., Faure-Dupuy, S., Riedl, T., Lange, S., Wisskirchen, K., Thiele, F., Cheng, C.-C., Yuan, D., Leone, V., Schmidt, R., Hünergard, J., Geisler, F., Unger, K., Algül, H., Schmid, R. M., Rad, R., Wedemeyer, H., Levrero, M., Protzer, U.,Heikenwalder, M. (2024)
  HBV-related HCC development in mice is STAT3 dependent and indicates an oncogenic effect of HBx. JHEP Rep. 2024;6(10):101128.
• Sigdel, T.K., Sur, S., Boada, P. et al. (2024)
  Proteome Analysis for Inflammation Related to Acute and Convalescent Infection. Inflammation 47, 346–362.

2023

• Fiedler MK, Drechsel J, Schmidt R, Luppa PB, Bach NC, Sieber SA. (2023)
  Rapid Diagnostic Platform for Personalized Vitamin B6 Detection in Erythrocytes via PLP Cofactor Mimics. ACS Chem Biol. 2023;18(7):1653-1660. 
• Galadima, M.; Kotova, I.; Schmidt, R.; Pastor, J.; Schröder, C.; Rodríguez-Gil, J.E.; del Alamo, M.M.R. (2023)
  Canine Mammary Neoplasia Induces Variations in the Peripheral Blood Levels of CD20, CD45RA, and CD99. 
  Int. J. Mol. Sci., 24, 9222. Int. J. Mol. Sci., 24, 9222.
• Vid Janša, Maja Pušić Novak, Helena Ban Frangež, Tea Lanišnik Rižner (2023)
  TGFBI as a candidate biomarker for non-invasive diagnosis of early-stage endometriosis.Hum Reprod. 2023;38(7):1284-1296.
• Kundu, S., Nunes, L., Adler, J. et al. (2023)
  Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells. Cell Commun Signal 21, 354 (2023).
• Romano A, Rižner TL, Werner HMJ, Semczuk A, Lowy C, Schröder C, Griesbeck A, Adamski J, Fishman D and Tokarz J (2023)
  Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: a systematic review. Front Oncol. 2023;13:1120178.
• Taylor, J., Uhl, L., Moll, I. et al. (2023)
  Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia. Nat Cancer 4, 1544–1560 (2023).
• Tintelnot, J., Xu, Y., Lesker, T.R. et al. (2023)
  Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer. Nature 615, 168–174 (2023).
• Wiedmann, L., De Angelis Rigotti, F., Vaquero-Siguero, N., Donato, E., Espinet, E., Moll, I., Alsina-Sanchis, E., Bohnenberger, H., Fernandez-Florido, E., Mülfarth, R., Vacca, M., Gerwing, J., Conradi, L. C., Ströbel, P., Trumpp, A., Mogler, C., Fischer, A., & Rodriguez-Vita, J. (2023) 
  HAPLN1 potentiates peritoneal metastasis in pancreatic cancer. Nat Commun. 2023;14(1):2353.

2022

• Abdulkhalikova D, Sustarsic A, Vrtačnik Bokal E, Jancar N, Jensterle M and Burnik Papler T. (2022)
  The Lifestyle Modifications and Endometrial Proteome Changes of Women With Polycystic Ovary Syndrome and Obesity. Front Endocrinol. 13:888460.
• Franz S, Ertel A, Engel KM, Simon JC, Saalbach A. (2022)
  Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing. Theranostics. 12(4):1659-1682. 
• Groetsch B., Schachtschabel E., Tripal P., Schmid B., Smith A., Schett G.A. and Bozec A. (2022)
  Inflammatory activation of FcgR and IFNgR pathways co-influence the differentiation and activity of osteoclasts. Front. Immunol. 13:958974.
• Labes R, Brinkmann L, Kulow VA, Roegner K, Mathia S, Balcerek B, Persson PB, Rosenberger C and Fähling M.  (2022)
  Daprodustat prevents cyclosporine-A mediated anemia and peritubular capillary loss. Kidney Int. S0085-2538(22)00375-1.
• Marino, D., Pizzi, M., Kotova, I., Schmidt, R., Schröder, C., Guzzardo, V., Talli, I., Peroni, E., Finotto, S., Scapinello, G., Dei Tos, A.P., Piazza, F., Trentin, L., Zagonel, V. and Piovan, E., (2022)
  High ETV6 Levels Support Aggressive B Lymphoma Cell Survival and Predict Poor Outcome in Diffuse Large B-Cell Lymphoma Patients. Cancers (Basel). 2022;14(2):338.
• Pušić M, Klančič T, Knific T, Vogler A, Schmidt R, Schröder Cand Lanišnik Rižner T. (2022)
  Antibody Arrays Identified Cycle-Dependent Plasma Biomarker Candidates of Peritoneal Endometriosis. J Pers Med. 12(6):852.
• Watson, C.N., Begum, G., Ashman, E., Thorn, D., Yakoub, K.M., Hariri, M.A., Nehme, A., Mondello, S., Kobeissy, F., Belli, A. and Di Pietro, V.,  (2022)
  Co-Expression Analysis of microRNAs and Proteins in Brain of Alzheimer’s Disease Patients. Cells. 2022;11(1):163.

2021

• Awwad, M.H.S., Mahmoud, A., Bruns, H., Echchannaoui, H., Kriegsmann, K., Lutz, R., Raab, M.S., Bertsch, U., Munder, M., Jauch, A., Weisel, K., Maier, B., Weinhold, N., Salwender, H.J., Eckstein, V., Hänel, M., Fenk, R., Dürig, J., Brors, B., Benner, A., Müller-Tidow, C., Goldschmidt, H., Hundemer, M., (2021)
  Selective elimination of immunosuppressive T cells in patients with multiple myeloma. Leukemia. 2021;35(9):2602‑2615.
• Fomitcheva-Khartchenko, A., Rapsomaniki, M.A., Sobottka, B., Schraml, P., Kaigala, G.V., (2021) 
  Spatial protein heterogeneity analysis in frozen tissues to evaluate tumor heterogeneity. PLoS One. 2021;16(11):e0259332.
• Janša, V., Klančič, T., Pušić, M., Klein, M., Vrtačnik Bokal, E., Ban Frangež, H., Rižner, T.L., (2021) 
  Proteomic analysis of peritoneal fluid identified COMP and TGFBI as new candidate biomarkers for endometriosis. Sci Rep. 2021;11(1):20870.
• Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté‐Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L.M., Su, J., Arias‐Fuenzalida, J., Walter, J., Gomez‐Giro, G., Monzel, A.S., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., Brunelli, F., Jäger, C., Rakovic, A., Li, W., Yuan, L., Berger, E., Arena, G., Bolognin, S., Schmidt, R., Schröder, C., Antony, P.M.A., Klein, C., Krüger, R., Seibler, P., Schwamborn, J.C., (2021)
  Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐CyclodextrinTreatment. Mov Disord. 2022;37(1):80‑94.
• Kowtharapu, B.S., Damaraju, J., Singh, N.K., Ziebart, J., Bader, R., Koczan, D., Stachs, O., (2021)
  Analysis of the Differential Gene and Protein Expression Profiles of Corneal Epithelial Cells Stimulated with Alternating Current Electric Fields. Genes. 2021;12(2):299.
• Lange, C., Weber, A.M., Schmidt, R., Schroeder, C., Strowitzki, T., Germeyer, A., (2021)
  Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line. PLoS One. 2021;16(3):e0248103.

2020

• Boberg, E., Kadri, N., Winterling, J., Davies, L.C., Björklund, A., Msghina, M., Iacobaeus, E., Le Blanc, K., (2020) 
  Mental fatigue after allogeneic hematopoietic stem cell transplantation is associated with cognitive dysfunction, but not central nervous system inflammation.
  Haematologica. 2020;105(6):e310‑e314.
• Fernando, R., Wardelmann, K., Deubel, S., Kehm, R., Jung, T., Mariotti, M., Vasilaki, A., Gladyshev, V.N., Kleinridders, A., Grune, T., Castro, J.P., (2020)
  Low steady-state oxidative stress inhibits adipogenesis by altering mitochondrial dynamics and decreasing cellular respiration. Redox Biol. 2020;32:101507.
• Fiorentino, F.P., Marchesi, I., Schröder, C., Schmidt, R., Yokota, J., Bagella, L., (2020)
  BET-Inhibitor I-BET762 and PARP-Inhibitor Talazoparib Synergy in Small Cell Lung Cancer Cells. Int J Mol Sci. 2020;21(24):9595.
• Yin, Y., Shelke, G.V., Lässer, C., Brismar, H., Lötvall, J., (2020)
  Extracellular vesicles from mast cells induce mesenchymal transition in airway epithelial cells. Respir Res. 2020;21(1):101.

2019 and older

• Fultang, L., Gamble, L.D., Gneo, L., Berry, A.M., Egan, S.A., De Bie, F., Yogev, O., Eden, G.L., Booth, S., Brownhill, S., Vardon, A., McConville, C.M., Cheng, P.N., Norris, M.D., Etchevers, H.C., Murray, J., Ziegler, D.S., Chesler, L., Schmidt, R., Burchill, S.A., Haber, M., De Santo, C., Mussai, F., (2019)
  Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma. Cancer Res. 2019;79(3):611‑624.
• Reichman, H., Itan, M., Rozenberg, P., Yarmolovski, T., Brazowski, E., Varol, C., Gluck, N., Shapira, S., Arber, N., Qimron, U., Karo-Atar, D., Lee, J.J., Munitz, A., (2019)
  Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer.
  Cancer Immunol Res 7, 388–400. Cancer Immunol Res. 2019;7(3):388‑400.
• Kowtharapu, B.S., Murín, R., Jünemann, A.G.M., Stachs, O., (2018)
  Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing. Int J Mol Sci. 2018;19(2):464.
• Peiro, J.L., Oria, M., Aydin, E., Joshi, R., Cabanas, N., Schmidt, R., Schroeder, C., Marotta, M., Varisco, B.M., (2018)
  Proteomic profiling of tracheal fluid in an ovine model of congenital diaphragmatic hernia and fetal tracheal occlusion. Am J Physiol Lung Cell Mol Physiol. 2018;315(6):L1028‑L1041.
• Thorenz, A., Derlin, K., Schröder, C., Dressler, L., Vijayan, V., Pradhan, P., Immenschuh, S., Jörns, A., Echtermeyer, F., Herzog, C., Chen, R., Rong, S., Bräsen, J.H., Kooten, C. van, Kirsch, T., Klemann, C., Meier, M., Klos, A., Haller, H., Hensen, B., Gueler, F., (2018)
  Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury–induced inflammation and fibrosis.
  Kidney Int. 2018;94(4):741‑755.
• Hamidi, Z., Tejero, E., Schmidt, R., Tucker, R., Pedro, A., (2017)
  Identification of potential blood-derived extracellular vesicles biomarkers to diagnose and predict distant metastases in ER+ breast cancer patients. bioRxiv 202291.
• Sass, F.A., Schmidt‐Bleek, K., Ellinghaus, A., Filter, S., Rose, A., Preininger, B., Reinke, S., Geissler, S., Volk, H.-D., Duda, G.N., Dienelt, A., (2017) 
  CD31+ Cells From Peripheral Blood Facilitate Bone Regeneration in Biologically Impaired Conditions Through Combined Effects on Immunomodulation and Angiogenesis.
  J Bone Miner Res. 2017;32(5):902‑912.
• Bakdash, G., Buschow, S.I., Gorris, M.A.J., Halilovic, A., Hato, S.V., Sköld, A.E., Schreibelt, G., Sittig, S.P., Torensma, R., Duiveman-de Boer, T., Schröder, C., Smits, E.L., Figdor, C.G., de Vries, I.J.M., (2016)
  Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines. Cancer Res. 2016;76(15):4332‑4343.

Selected Scientific Publications by the Sciomics Team 

• Fiedler MK, Drechsel J, Schmidt R, Luppa PB, Bach NC, Sieber SA. (2023)
  Rapid Diagnostic Platform for Personalized Vitamin B6 Detection in Erythrocytes via PLP Cofactor Mimics. ACS Chem Biol. 2023;18(7):1653-1660.
• Galadima, M.; Kotova, I.; Schmidt, R.; Pastor, J.; Schröder, C.; Rodríguez-Gil, J.E.; del Alamo, M.M.R. (2023)
  Canine Mammary Neoplasia Induces Variations in the Peripheral Blood Levels of CD20, CD45RA, and CD99. 
  Int. J. Mol. Sci., 24, 9222. Int. J. Mol. Sci., 24, 9222.
• Hufnagel, K., Fathi, A., Stroh, N., Klein, M., Skwirblies, F., Girgis, R., Dahlke, C., Hoheisel, J. D., Lowy, C., Schmidt, R., Griesbeck, A., Merle, U., Addo, M. M., & Schröder, C. (2023)
  Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease. Commun Med (Lond). 2023;3:51.
• Marino, D., Pizzi, M., Kotova, I., Schmidt, R., Schröder, C., Guzzardo, V., Talli, I., Peroni, E., Finotto, S., Scapinello, G., Dei Tos, A.P., Piazza, F., Trentin, L., Zagonel, V., Piovan, E. (2022)
  High ETV6 Levels Support Aggressive B Lymphoma Cell Survival and Predict Poor Outcome in Diffuse Large B-Cell Lymphoma Patients.  Cancers (Basel). 2022;14(2):338.
• Jarazo, J., Barmpa, K., Modamio, J., Saraiva, C., Sabaté‐Soler, S., Rosety, I., Griesbeck, A., Skwirblies, F., Zaffaroni, G., Smits, L.M., Su, J., Arias‐Fuenzalida, J., Walter, J., Gomez‐Giro, G., Monzel, A.S., Qing, X., Vitali, A., Cruciani, G., Boussaad, I., Brunelli, F., Jäger, C., Rakovic, A., Li, W., Yuan, L., Berger, E., Arena, G., Bolognin, S., Schmidt, R., Schröder, C., Antony, P.M.A., Klein, C., Krüger, R., Seibler, P., Schwamborn, J.C. (2022) 
  Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐CyclodextrinTreatment. Mov Disord. 2022;37(1):80‑94.
• Pušić M, Klančič T, Knific T, Vogler A, Schmidt R, Schröder C, Lanišnik Rižner T. (2022)
  Antibody Arrays Identified Cycle-Dependent Plasma Biomarker Candidates of Peritoneal Endometriosis. J Pers Med. 12(6):852.
• Janša, V., Klančič, T., Pušić, M., Klein, M., Vrtačnik Bokal, E., Ban Frangež, H., Rižner, T.L. (2021) 
  Proteomic analysis of peritoneal fluid identified COMP and TGFBI as new candidate biomarkers for endometriosis. Sci Rep. 2021;11(1):20870.
• Lange, C., Weber, A.M., Schmidt, R., Schroeder, C., Strowitzki, T., Germeyer, A. (2021)
  Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line. PLoS One. 2021;16(3):e0248103.
• Fiorentino, F.P., Marchesi, I., Schröder, C., Schmidt, R., Yokota, J., Bagella, L. (2020) 
  BET-Inhibitor I-BET762 and PARP-Inhibitor Talazoparib Synergy in Small Cell Lung Cancer Cells. Int J Mol Sci. 2020;21(24):9595.
• Fultang, L., Gamble, L.D., Gneo, L., Berry, A.M., Egan, S.A., Bie, F.D., Yogev, O., Eden, G.L., Booth, S., Brownhill, S., Vardon, A., McConville, C.M., Cheng, P.N., Norris, M.D., Etchevers, H.C., Murray, J., Ziegler, D.S., Chesler, L., Schmidt, R., Burchill, S.A., Haber, M., Santo, C.D., Mussai, F. (2019) 
  Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma. Cancer Res. 2019;79(3):611‑624.
• Thorenz, A., Derlin, K., Schröder, C., Dressler, L., Vijayan, V., Pradhan, P., Immenschuh, S., Jörns, A., Echtermeyer, F., Herzog, C., Chen, R., Rong, S., Bräsen, J.H., Kooten, C. van, Kirsch, T., Klemann, C., Meier, M., Klos, A., Haller, H., Hensen, B., Gueler, F. (2018) 
  Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury–induced inflammation and fibrosis.
  Kidney Int. 2018;94(4):741‑755.
• Peiro, J.L., Oria, M., Aydin, E., Joshi, R., Cabanas, N., Schmidt, R., Schroeder, C., Marotta, M., Varisco, B.M. (2018) 
  Proteomic profiling of tracheal fluid in an ovine model of congenital diaphragmatic hernia and fetal tracheal occlusion. Am J Physiol Lung Cell Mol Physiol. 2018;315(6):L1028‑L1041.
• Bakdash, G., Buschow, S.I., Gorris, M.A.J., Halilovic, A., Hato, S.V., Sköld, A.E., Schreibelt, G., Sittig, S.P., Torensma, R., Boer, T.D., Schröder, C., Smits, E.L., Figdor, C.G., de Vries, I.J.M. (2016)
  Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines. Cancer Res. 2016;76(15):4332‑4343.
• Kibat, J., Schirrmann, T., Knape, M.J., Helmsing, S., Meier, D., Hust, M., Schröder, C., Bertinetti, D., Winter, G., Pardes, K., Funk, M., Vala, A., Giese, N., Herberg, F.W., Dübel, S., Hoheisel, J.D. (2016).
  Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality. New Biotechnol. 2016;33(5 Pt A):574‑581.
• Betzen, C., Alhamdani, M.S.S., Lueong, S., Schröder, C., Stang, A., Hoheisel, J.D. (2015) 
  Clinical proteomics: Promises, challenges and limitations of affinity arrays. Proteomics Clin Appl. 2015;9(3‑4):342‑347.
• Nijaguna, M.B., Schröder, C., Patil, V., Shwetha, S.D., Hegde, A.S., Chandramouli, B.A., Arivazhagan, A., Santosh, V., Hoheisel, J.D., Somasundaram, K. (2015) 
  Definition of a serum marker panel for glioblastoma discrimination and identification of Interleukin 1β in the microglial secretome as a novel mediator of endothelial cell survival induced by C-reactive protein. J Proteomics. 2015;128:171‑182.
• Srinivasan, H., Allory, Y., Sill, M., Vordos, D., Alhamdani, M.S.S., Radvanyi, F., Hoheisel, J.D., Schröder, C. (2014) 
  Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses. Proteomics. 2014;14(11):1333‑1342.
• Hoheisel, J.D., Alhamdani, M.S.S., Schröder, C. (2013) 
  Affinity-based microarrays for proteomic analysis of cancer tissues. Proteomics Clin Appl. 2013;7(1‑2):8‑15.
• Schröder, C., Srinivasan, H., Sill, M., Linseisen, J., Fellenberg, K., Becker, N., Nieters, A., Hoheisel, J.D. (2013) 
  Plasma protein analysis of patients with different B-cell lymphomas using high-content antibody microarrays. Proteomics Clin Appl. 2013;7(11‑12):802‑812.
• Alhamdani, M.S.S., Youns, M., Buchholz, M., Gress, T.M., Beckers, M.-C., Maréchal, D., Bauer, A., Schröder, C., Hoheisel, J.D. (2012) 
  Immunoassay-based proteome profiling of 24 pancreatic cancer cell lines. J Proteomics. 2012;75(12):3747‑3759.
• Alhamdani, M.S.S., Schröder, C., Hoheisel, J.D. (2010) 
  Analysis conditions for proteomic profiling of mammalian tissue and cell extracts with antibody microarrays. Proteomics. 2010;10(17):3203‑3207.
• Alhamdani, M.S.S., Schröder, C., Werner, J., Giese, N., Bauer, A., Hoheisel, J.D. (2010).
  Single-Step Procedure for the Isolation of Proteins at Near-Native Conditions from Mammalian Tissue for Proteomic Analysis on Antibody Microarrays. J Proteome Res. 2010;9(2):963‑971.
• Schröder, C., Jacob, A., Tonack, S., Radon, T.P., Sill, M., Zucknick, M., Rüffer, S., Costello, E., Neoptolemos, J.P., Crnogorac-Jurcevic, T., Bauer, A., Fellenberg, K., Hoheisel, J.D. (2010).
  Dual-color Proteomic Profiling of Complex Samples with a Microarray of 810 Cancer-related Antibodies. Mol Cell Proteomics. 2010;9(6):1271‑1280.
• Sill, M., Schröder, C., Hoheisel, J.D., Benner, A., Zucknick, M. (2010).
  Assessment and optimisation of normalisation methods for dual-colour antibody microarrays. BMC Bioinformatics. 2010;11:556.
• Kusnezow, W., Banzon, V., Schröder, C., Schaal, R., Hoheisel, J.D., Rüffer, S., Luft, P., Duschl, A., Syagailo, Y.V. (2007).
  Antibody microarray-based profiling of complex specimens: systematic evaluation of labeling strategies. Proteomics. 2007;7(17):1786‑1799.

Presentations at Scientific Conferences 

2023

Alenazi, F., Schmidt, R., Schroder, C. et al (2023)
14 Metformin does not reverse the effect of pharmacological inhibition of protein phosphatase 2A on VE-cadherin in human microvascular endothelial cells
Heart 2023;109:A5. Scottish Cardiovascular Forum – 26th annual meeting

Ceton, L., Koedoot, E., Sijsenaar, T., Montero Garcia, M., Grillet, F., van der Valk, J., Weber, K., Schoenauer, R., Hufnagel, K., Schmidt, R., Stroh, N., Boekhoff, H., de Kroon, C., van Altena, A., van der Meer, D., Vader, W., Ottevanger, N., Kroep, J. (2023)
Interpretation of patient-specific ex vivo immunotherapy response for ovarian cancer [abstract].
Proceedings of the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics; 2023 Oct 11-15; Boston, MA. Philadelphia (PA): AACR; 
Mol Cancer Ther. 2023;22(12 Suppl):Abstract nr PR001.

Kenzelmann, A., Boch, C., Schulz, M., Challagundla, M., Just, D.,Klein, M., Griesbeck, A., Schroeder, C. and Richter, M.(2023) Exploration of novel biomarkers for neurodegenerative diseases using ligand-binding assays. Alzheimer’sDement.2023;19(Suppl.14):e076362, presented at the Alzheimer's Association International Conference (AAIC) 2023, July 16-20, Amsterdam, Netherlands; a collaboration of AbbVie and Sciomics 

Kokol, M., Romano, A., Werner, E. et al (2023)
#383 BioEndoCar: identifying candidate biomarkers for diagnosis and prognosis of endometrial carcinoma using machine learning and artificial intelligence 
International Journal of Gynecologic Cancer 2023;33:A368. ESGO 2023 Congress

Swiatek-de Lange, M., Schroeder, C., Klein, M., Huang, J. and Strobl, M. (2023) 
Identification of biomarkers for prediction of dengue deterioration, presented at 6th Asia Dengue Summit (ADS 2023), 15-16 June 2023, Bangkok, Thailand; a collaboration of Roche Diagnostics and Sciomics

Xu, S., Schulz, M., Schmidt, R., Richter, M., Klein, M., Hufnagel, K., Schroeder, C. and Scolnick, J. (2023)
Increased monocyte activity identified in Alzheimer’s disease by in depth single-cell genomic and proteomic analysis. Alzheimer's Dement., 19: e071084 , presented at the Alzheimer's Association International Conference (AAIC) 2023, July 16-20, Amsterdam, Netherlands; a collaboration of Singleron Biotechnologies, AbbVie and Sciomics

2022

Schmidt, R., Schwamborn, J., Klein, M., Richter, M., Schulz, M. and Schroeder, C. (2022)
In-depth molecular profiling of Parkinson’s disease using advanced Minibrain models, presented at the International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD 2022), March 15-20, Barcelona, Spain, a collaboration of AbbVie, OrganoTherapeutics and Sciomics 

2021

Hafner, E., Smrkolj, Š., Romano, Werner, H. M. J., Semczuk, A., Kaminska, A., Adamiak-Godlewska, A., Fishman, D., Vilo, J., Lowy, C., Schröder, C., Janina Tokarz, J., Adamski, J., Weinberger, V., Bednaříková, M., Vinklerova, P., Ferrero, S., Barra, F., Takač, I., Knez, J., Lanišnik Rižner T. (2021)
BioEndoCar: in search of new Biomarkers for Diagnosis and Prognosis of Endometrial Carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 464. 

Schroeder, C., Schmidt, R., Klein, M., Griesbeck, A., Richter, M., Schulz, M. (2021)
Identification of new biomarker signatures for neurodegenerative diseases, presented at the International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD 2021), a collaboration of AbbVie and Sciomics  

Selected Patents with Contribution of our Microarray Platform

• WO2021175863A1: Method for diagnosis and/or prognosis of liver disease progression and risk of hepatocellular carcinoma and discovery of therapeutic compounds and targets to treat liver disease and cancer
• WO2021162554A1: Means and methods for determining mesenchymal stromal cell properties.
• US20210137912A1: s)-2-(1-(5-(cyclohexylcarbamoyl)-6-(propylthio)pyridin-2-yl)piperidin-3-yl)acetic acid for use in medicine
• EP2536844B1, US9551035B2: Means and methods for diagnosing pancreatic cancer
• EP2718720B1, US9678075B2: Prediction of recurrence for bladder cancer by a protein signature in tissue samples