Proteomics service for pre-clinical research &

Protein biomarker discovery

Robust, comprehensive & fast

Our high-throughput protein profiling service supports researchers in identifying novel protein biomarkers, understanding disease mechanisms, and accelerating pre-clinical drug development.

Using our proprietary antibody microarray platform, we enable the simultaneous quantification of over 1,500 proteins from minimal sample volumes — ideal for biomarker discovery, pathway analysis, and protein profiling studies.

Partner with Sciomics – your specialized proteomics CRO – and take your biomarker discovery and pre-clinical research to the next level.

   

    Biomarker discovery
 in research blog         Speak with
 a scientist   

The Assay

• High-throughput immuno-based protein profiling using complex antibody microarrays
• Ideal for pre-clinical protein biomarker discovery and pathway analysis
• Broad coverage of key biological processes and signaling pathways
• Native sample matrices (non-fractionated / non-depleted)
• Highest sensitivity and reproducibility (CV <10%, 4 technical replicates) from minimal sample volumes

 As your trusted CRO partner for immunobased proteomics, we offer end-to-end support – from study planning and sample analysis to comprehensive data interpretation. Whether you're exploring disease mechanisms or validating drug effects, our platform delivers actionable insights for your research success.

 

     Speak with
 a scientist   

 

Data Analysis is included

• In-depth bioinformatic analysis based on > 6,000 data points per sample
• Protein interaction and pathway network mapping
• Functional annotation and biological pathway classification
• Data integration for different sample types

Application examples

• Protein biomarker discovery
• Pre-clinical and translational research
• Pathway profiling and pathway regulation studies
• Drug response profiling and mode-of-action studies
• Patient stratification 
• Basic research 

Compatible sample types

Our service supports a broad range of sample types – even in very limited amounts:

• Plasma / Serum
• Cerebrospinal fluid (CSF)
• Interstitial fluid (ISF)
• Urine
• Saliva
• Tissue lysates
• Cell lysates / cultured cells
• Cell culture supernatants
• Organoids

If you are working with a different type of biological sample, feel free to contact our scientists – we are generally able to analyse any protein-containing sample

scioDiscover - In depth profiling on the protein level

scioUbi: protein profiling and ubiquitination status

scioPhospho: phosphoproteomics and protein profiling service

scioCD - Cell Surface Marker and Cytokine Profiling

scioCyto : Cytokine Profiling

Protein abundance and phosphorylation analysis in one step by our high-throughput scioPhospho platform.

Simultaneous detection of protein levels & phosphorylation status of > 1,500 proteins.

Our scioPhospho protein phosphorylation analysis service combines protein profiling using scioDiscover with analysis of the corresponding protein phosphorylation status. More than 1,500 proteins are analyzed in parallel, covering key pathways in diseases such as cancer, neurological disorders and organ failure.  This combination provides a comprehensive overview of cellular signaling and pathway activity regulation in your samples.

Thereby, scioPhosho enables a fast and cost-effective in-depth protein and phosphorylation analysis from minute amounts of human biospecimen, organoid models, cell cultur models or animal models. Our full phospho-proteomic analysis service includes expert data analysis and generates knowledge on protein and protein phosphorylation level. This is highly valuable for our clients in preclinical research interested in activity-based protein profiling.

 

   

   Article in
  our research blog        Discuss your project
 with a scientist   

The Assay:

• Phosphorylation and protein expression in a direct comparison in one assay
• Coverage of key signalling pathways 
• Analysis of various sample types with minimal sample amounts
• Native matrices (non-fractionated / non-depleted)
• 4 replicates for each antibody
• High reproducibility (CV < 10%)

 

Applications

• Pathway analysis / Pathway regulation
• Mode-of-action studies
• Drug response profiling
• Disease mechanism screening
• Biomarker discovery
• Validation of predicted protein phosphorylation

Data Analysis is included

• Comprehensive data analysis using a basis of > 12,000 data points for each sample
• Differential proteomics and phosphoproteomics
• Protein interaction network analysis
• Biological and pathway classification

Phospho-proteomic studies

• Characterisation of a Parkinson Organoid Model in terms of protein secretion as well as intracellular effects
  Poster presented at ADPD 2022
• Phosphoproteomic anaylsis of osteoclasts differentiated from human peripheral blood
  Front. Immunol. 13:958974 
• Protection of  kidney toxicity and anemia by preventing protein phosphorylation changes
  Kidney Int. (2022)102(4):750-765.
• Characterisation of protective effect of Complement component 5a receptor 2 in ischemia reperfusion injury
  Kidney International (2018) 94, 741–755.
• Analysis of BET and PARP inhibitor synergy in Small Cell Lung Cancer cellular model
  Int J Mol Sci (2020) 21