scioUbi

Protein & ubiquitination profiling

scioUbi is a high-content protein expression and ubiquitination level analysis.
With scioUbi you can analyse up to 1,000 proteins in a single assay.

 

Features

  • Ubiquitination status for more than 1,000 proteins in parallel
    in a single assay
  • 4 technical replicates per sample
  • Comprehensive data analysis and presentation including
    an individualised report
  • Customisation of ubiquitin detection on request

Benefits for your research

  • Two in one: High-content protein expression and ubiquitination level analysis in a single assay
  • Proteins selected for biomedical studies: Central regulators (e.g. mTor, p53), transcription factors, receptors
  • Minimal sample (e.g. tissue or cell culture samples) amounts needed for complete analysis
sciomics scioUbi Ubiquitination And Protein Profiling Biological processes selection of proteins
Biological processes		   sciomics scioUbi Ubiquitination And Protein Profiling Cell Cycle proteins coveredCell cycle: proteins in green are covered by the analysis

 

Applications

Biological effects of

  • protein degradation in health and disease
  • protein activity changes
  • protein interaction alterations
  • drug response (e.g. proteasome enhancers)

Others

  • Interplay between ubiquitination and phosphorylation (see scioPhospho)
  • Neurodegenerative diseases
  • Progression of ageing
  • Cell cycle regulation
  • Proteasome activity
  • Transcriptional regulation
  • p53 pathway regulation
  • Alzheimer pathway regulation

 

Contact us

 

 

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Our service portfolio

scioPhospho: protein profiling and phosphorylation status

scioPhospho: protein profiling and phosphorylation status
scioPhospho combines the advantages of a robust and cost-efficient protein expression profiling using scioDiscover with information on phosphorylation status. This combination provides a comprehensive overview on signalling events and pathway activity regulation. Features 1030 highly relevant proteins are profiled in a single assay Phosphorylation status combined with protein expression levels Tyrosine,…
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scioDiscover - Protein Profiling on expression level

scioDiscover - Protein Profiling on expression level
Knowledge about protein expression levels is of utmost importance to predict toxic effects, estimate adverse effects of drug candidates and to identify new drug targets. Sciomics has a highly optimised…
scioCD - Cell surface marker and Cytokine profiling

scioCD - Cell surface marker and Cytokine profiling
  Characterise a certain cell type?   Cell composition in a certain tissue sample?   In-depth profiling of CD-marker expression?   Increase your throughput at high sensitivity levels? You aim…
scioCyto

scioCyto
Cytokine profiling scioCyto is a high-content analysis service for cytokine and chemokine profiling on protein level. A great variety of samples such as plasma, tissue, cells or cell cultur supernatants…
scioUbi

scioUbi
Protein & ubiquitination profiling scioUbi is a high-content protein expression and ubiquitination level analysis. With scioUbi you can analyse up to 1,000 proteins in a single assay.   Features Ubiquitination…

News

New article | Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer

| Jan 2019 | In the article, scientists at Tel Aviv University used our scioDiscover platform to analyse tumor-associated eosinophils in colorectal cancer. The full article is published in Cancer Immunology Research.

 
New article | Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma

| Decembre 2018 | Study by our collaborator Dr Francis Mussai at University of Birmingham suggests arginine metabolism as a target for neuroblastoma therapy. At Sciomics we are proud of having contributed to this exciting study by a scioDiscover protein profiling study. The article is published in Cancer Research.

 
New article | Protection from ischemia reperfusion injury-induced inflammation and fibrosis in C5aR2-deficient mice

| June 2018 | Complement component 5a receptor 2 (C5AR2) deficient mice are protected from inflammation and fibrosis in response to ischemia reperfusion injury. Our scioPhospho platform supported scientists at the Medical School Hannover to elucidate the underlying mechanism. The data were recently published in Kidney International.

 
New article | Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

| January 2018 | A scioDiscover protein microarray study contributed to an article in Cell Reports. In this study Gerard Ruiz-Babot et al. analysed a donor specific reprogramming of cells.

Customer testimonial Leonardo Guasti, PhD (senior author):

This has undoubtedly opened new avenues in our research. We have found the Sciomics team to be extremely helpful and efficient during the whole process, from advising the best strategy to the final interpretation of results.

> More testimonials
A glas full of hope | Ein Glas Hoffnung

| January 2018 | Article on the StartUp Sciomics and our antibody microarray platform by our partner SCHOTT nexterion.

> English version "A glass full of hope"

> Deutsche Version "Ein Glas Hoffnung"

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