scioDiscover - Drug Target Discovery

 

You identified a compound with the desired effect ?

 

You are looking for its target(s) ?

Which additional pathways are affected ?

Which proteins are altered in a diseased tissue ?

 

Get the whole picture of protein expression in multiple pathways !

 

 

 

Profound knowledge about protein expression levels is of utmost importance for the discovery and evaluation of new drug targets. Our Scio-Discover Service is fully immuno-based and covers proteins involved in major disease and signalling pathways as well as secreted proteins. For the highly-parallel protein analysis only minimal amounts of sample are required. No sample fractionation or depletion is needed. Our platform is able to process most biological samples without the need for laborious sample preparation, saving time and resources.

 

Applications:

  • Drug Target Identification and verification studies
  • Mechanistic studies for various indications
  • Correlate Next-Gen-Sequencing Data to protein expression levels
  • Profile cytokine and inflammatory status of your samples

 

Key advantages:

  • Low sample consumption 
  • Investigation of human and murine samples*
  • Fast turnaround time, as low as two weeks**
  • No need for laborious depletion or fractionation of your samples
  • High sensitivity (as sensitive as an ELISA or better)
  • High reproducibility (CV < 10%)
  • Various sample types can be investigated
    • Serum / Plasma
    • Tissue
    • Cell culture
    • Cerebrospinal fluid (CSF)

 

Service Features:

  • Study Layout
  • Protein Extraction and Purification
  • Protein Quantification
  • Protein labelling with high-performance fluorescent dyes
  • Automated array incubation and handling 
  • Array scanning and data acquisition
  • Data analysis according to your requirements
  • Individual study report

 

Overview
Scio-Discover
    Array
Content
    Biomarker
Discovery
    Contact
us

 

 

* other species on request

** depending on study design and sample numbers

 

 

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Our service portfolio

scioPhospho: protein profiling and phosphorylation status

scioPhospho: protein profiling and phosphorylation status

scioPhospho combines the advantages of a robust and cost-efficient protein expression profiling using scioDiscover with information on phosphorylation status. This combination provides a comprehensive overview on signalling events and pathway activity regulation. Features 900 highly relevant proteins are profiled in a single assay Phosphorylation status combined with protein expression levels…
Read more
scioDiscover - Protein Profiling on expression level

scioDiscover - Protein Profiling on expression level

Knowledge about protein expression levels is of utmost importance to predict toxic effects, estimate adverse effects of drug candidates and to identify new drug targets. Sciomics has a highly optimised…
scioSpot - Microarray Production

scioSpot - Microarray Production

Microarrays - tailor-made for you. With more than 10 years of experience, Sciomics is the ideal partner for designing and printing your antibody-, protein-, peptide- or DNA/RNA chips. Benefit from…
scioCD - Cell surface marker and Cytokine profiling

scioCD - Cell surface marker and Cytokine profiling

Characterise a certain cell type ? Cell composition in a certain tissue sample ? In-depth profiling of CD-marker expression ? Increase your throughput at high sensitivity levels ? You aim…

News

New article | Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing

| February 2018 | Researchers at Rostock University Medical Center published an article on the role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing in the International Journal of Molecular Sciences.

> Customer Testimonial Bhavani Kowtharapu:

"I am really happy with service of Sciomics. Very friendly team and really fast service and we have the results in our hand including bioinformatics analysis within 2 weeks. Thank you Sciomics team."

> More testimonials

Meeting | Sciomics @ BIO-Europe Spring

| March 12-14 2018 | Meet Dr. Christoph Schröder at BIO-Europe Spring in Amsterdam to learn about the benefit of pathway activity profilings in pre-clinical research. Our scioPhospho service combines the analysis of protein levels of more than 1,000 proteins with the knowledge on the phosphorylation status and thereby enables profound insights in the activity of the major biomedical pathways.

Meeting | Sciomics @ Int. Conference on Perspectives in Precision Medicine

| February 28 - March 1 2018 | Meet Dr. Ronny Schmidt at the International Conference on Perspectives in Precision Medicine in Copenhagen to learn how Sciomics can support you in the identification and verification of protein biomarkers for precision medicine.

Research | Participation in collaborative clinical studies for the treatment of MCDS

| January 2018 | The multinational consortium MCDS-therapy has been granted 5.7 Million Euro by the European Commission for the development of novel therapeutic approaches in rare skeletal disorders. Sciomics' expertise with the antibody microarray technology herein serves as a valuable tool for biomarker identification and personalized treatment monitoring. > Press release

New article | Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

| January 2018 | A scioDiscover protein microarray study contributed to an article in Cell Reports. In this study Gerard Ruiz-Babot et al. analysed a donor specific reprogramming of cells.

Customer testimonial Leonardo Guasti, PhD (senior author):

This has undoubtedly opened new avenues in our research. We have found the Sciomics team to be extremely helpful and efficient during the whole process, from advising the best strategy to the final interpretation of results.

> More testimonials

A glas full of hope | Ein Glas Hoffnung

| January 2018 | Article on the StartUp Sciomics and our antibody microarray platform by our partner SCHOTT nexterion.

> English version "A glass full of hope"

> Deutsche Version "Ein Glas Hoffnung"

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