scioCyto is a high-content analysis service for cytokine and chemokine profiling. A great variety of samples such as plasma, tissue or cells can be used in this robust assay for complete analysis: from protein extraction to data interpretation.
scioPhospho combines the advantages of a robust and cost-efficient protein expression profiling using scioDiscover with information on phosphorylation status. This combination provides a comprehensive overview on signalling events and pathway activity regulation. Features 1030 highly relevant proteins are profiled in a single assay Phosphorylation status combined with protein expression levels…
Knowledge about protein expression levels is of utmost importance to predict toxic effects, estimate adverse effects of drug candidates and to identify new drug targets. Sciomics has a highly optimised…
Analyze 54 cytokines and chemokines in parallel Uniprot Entry HGNC Gene names (synonym) Uniprot ID Protein names CCL2_HUMAN CCL2 MCP1, SCYA2 P13500 C-C motif chemokine 2 (HC11) (Monocyte chemoattractant…
New article | Activated Eosinophils Exert Antitumorigenic Activities in Colorectal Cancer
| Jan 2019 | In the article, scientists at Tel Aviv University used our scioDiscover platform to analyse tumor-associated eosinophils in colorectal cancer. The full article is published in Cancer Immunology Research.
New article | Macrophage-derived IL-1β and TNF-α regulate arginine metabolism in neuroblastoma
| Decembre 2018 | Study by our collaborator Dr Francis Mussai at University of Birmingham suggests arginine metabolism as a target for neuroblastoma therapy. At Sciomics we are proud of having contributed to this exciting study by a scioDiscover protein profiling study. The article is published in Cancer Research.
New article | Protection from ischemia reperfusion injury-induced inflammation and fibrosis in C5aR2-deficient mice
| June 2018 | Complement component 5a receptor 2 (C5AR2) deficient mice are protected from inflammation and fibrosis in response to ischemia reperfusion injury. Our scioPhospho platform supported scientists at the Medical School Hannover to elucidate the underlying mechanism. The data were recently published in Kidney International.
New article | Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells
| January 2018 | A scioDiscover protein microarray study contributed to an article in Cell Reports. In this study Gerard Ruiz-Babot et al. analysed a donor specific reprogramming of cells.
This has undoubtedly opened new avenues in our research. We have found the Sciomics team to be extremely helpful and efficient during the whole process, from advising the best strategy to the final interpretation of results.
Research | Participation in collaborative clinical studies for the treatment of MCDS
| January 2018 | The multinational consortiumMCDS-therapy has been granted 5.7 Million Euro by the European Commission for the development of novel therapeutic approaches in rare skeletal disorders. Sciomics' expertise with the antibody microarray technology herein serves as a valuable tool for biomarker identification and personalized treatment monitoring. > Press release