scioSpec - Antibody Specificity Assessment

Be sure that your antibody is fit for your application. Profile your therapeutic or diagnostic antibody against more than 9000 human proteins. Have a comprehensive cross-reactivity and off-target reactivity profile at hand. Our comprehensive antibody specificity screening service offers you a tailored study design, experimental conditions according to your requirements as well as comprehensive data and statistical analysis. Benefit from our long-standing experience in the microarray field and robust, fully-automated experimental workflows. 

    

Features

  • Comprehensive sample-to-result analysis service including data analysis
  • Comprehensive data analysis and report formats available
  • Customer specific Study Design Service available 
  • Fully automated experimental procedures
  • Highly parallel screening against more than 9.000 human proteins
  • Proteins carry eukaryotic post translational modifications (PTM)
  • All protein classes covered within the analysis

 

Applications

  • Comprehensive therapeutic and diagnostic antibody specificity/reactivity profiling
  • Profile off-target interactions and cross reactions of your antibody
  • Profile interactions with related proteins (e.g. kinases, cell surface proteins, CD marker)
  • Determine therapeutically relevant interactions

 

 

Overview of protein classes covered within the analysis service:

Download complete protein content list here

Protein Class

No. on array

Protein kinases (unique)

268

Protein kinases (including domains, splice variants and mutants)

776

Transcription factors

328

Membrane protins

2,635

Nuclear proteins

2,252

Signal transduction

1,526

Secreted proteins

192

Cell communication

1,687

Metabolism

3,862

Cell death

505

Protease/peptidase activity

219

Please note: Protein classes may overlap.

 

For further and more detailed information This email address is being protected from spambots. You need JavaScript enabled to view it..

 

 

 

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News

New article | Protection from ischemia reperfusion injury-induced inflammation and fibrosis in C5aR2-deficient mice

| June 2018 | Complement component 5a receptor 2 (C5AR2) deficient mice are protected from inflammation and fibrosis in response to ischemia reperfusion injury. Our scioPhospho platform supported scientists at the Medical School Hannover to elucidate the underlying mechanism. The data were recently published in Kidney International.

 

New article | Role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing

| February 2018 | Researchers at Rostock University Medical Center published an article on the role of Corneal Stromal Cells on Epithelial Cell Function during Wound Healing in the International Journal of Molecular Sciences.

> Customer Testimonial Bhavani Kowtharapu:

"I am really happy with service of Sciomics. Very friendly team and really fast service and we have the results in our hand including bioinformatics analysis within 2 weeks. Thank you Sciomics team."

> More testimonials

Research | Participation in collaborative clinical studies for the treatment of MCDS

| January 2018 | The multinational consortium MCDS-therapy has been granted 5.7 Million Euro by the European Commission for the development of novel therapeutic approaches in rare skeletal disorders. Sciomics' expertise with the antibody microarray technology herein serves as a valuable tool for biomarker identification and personalized treatment monitoring. > Press release

New article | Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

| January 2018 | A scioDiscover protein microarray study contributed to an article in Cell Reports. In this study Gerard Ruiz-Babot et al. analysed a donor specific reprogramming of cells.

Customer testimonial Leonardo Guasti, PhD (senior author):

This has undoubtedly opened new avenues in our research. We have found the Sciomics team to be extremely helpful and efficient during the whole process, from advising the best strategy to the final interpretation of results.

> More testimonials

A glas full of hope | Ein Glas Hoffnung

| January 2018 | Article on the StartUp Sciomics and our antibody microarray platform by our partner SCHOTT nexterion.

> English version "A glass full of hope"

> Deutsche Version "Ein Glas Hoffnung"

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