Partners & Networks

Partners

 

Animal models

 

 

Phenos GmbH

Contract research organisation offering services and research expertise to pharmaceutical companies and academia. PHENOS core expertise is the physiological and pathological analysis of mice and rat models. Using its long lasting experience in in-vivo models, Phenos provides its sophisticated expertise in three major areas:

  • Phenotypical analysis of genetic altered mice (e.g. knock-out animals)
  • Preclinical in-vivo evaluation of new drug compounds
  • Identification of new therapeutic strategies of approved drugs
  • Animal models for the study of kidney disease

 

Cell-Based Assay Services

 

 

Kitos biotech s.r.l.s.

Cell-Based Assay Services for Anticancer Drug Discovery Research.

The goal of Kitos is to assist customers in discovering innovative therapeutic products in an efficient, cost effective manner. ​Kitos has a well-equipped facility with cutting-edge technologies and a team of expert and dedicated scientists.

 

Antibody Specificity Assessment

 

 

Cambridge Protein Arrays Ltd.

Cambridge Protein arrays is a CRO offering analysis services based on complex human protein arrays. While the antibody arrays of Sciomics can be used to profile the content of proteins in a sample, recombinant protein arrays are especially useful for the interpretation of binding parameters of antibodies or auto-antibodies to a human proteins. Such arrays provide ultimate insights in the specificity of an antibody and information on eventual cross-binding events.

   

PEPperPRINT GmbH

Pepperprint offers standard and customized peptide microarrays with their proprietary LASER peptide printing technology which combines high spot densities with content flexibility, production speed and quality in a uniquely cost-effective manner. 
 

 

Recombinant antibodies

 

  
   

YUMAB GmbH

YUMAB provides tailored solutions for human antibody development and antibody engineering problems. YUMAB provides rapid, large-scale discovery and optimization of human monoclonal antibodies, custom libraries, antibody engineering (e.g., humanization, affinity maturation, various antibody product formats), and custom-made antibodies to difficult antigen targets. YUMAB offers fee-for-service solutions, and attractive and flexible licensing options for diagnostics and therapeutics. 

 

Instrumentation

 

 

DITABIS AG

DITABIS entwickelt und fertigt auf der Basis von OEM-Partnerschaften Medizingeräte, Laborgeräte oder Imagingsysteme für Anwendungen in den Bereichen Health Care, Life Science und In-Vitro-Diagnostik.

 

 

 

 

 Research projects

 

 

MCDS-Therapy (@MCDS-Therapy)

A Horizon 2020 funded 5-year clinical trial for the repurposing of carbamazepine for the treatment of metaphyseal chondrodysplasia, type Schmid.

> Read our press release

     

 

 

 

Networks

 

 

BIO Deutschland

As the sector association of the biotechnology industry, BIO Deutschland has set itself the objective of supporting and promoting the development of an innovative economic sector based on modern biosciences.

   

DECHEMA

DECHEMA is the expert network for chemical engineering and biotechnology in Germany. As a non-profit professional society we represent these fields in science, industry, politics and the general public. DECHEMA promotes scientific and technical exchange among experts from different disciplines, organisations and generations. We consolidate the know-how of over 5,800 individual and sustaining members.

 

BioRN

Over the past few years the Rhine-Neckar biotech region has developed into one of Germany’s strongest biotechnology clusters. The cluster is located within a radius of 30 km around the cities of Heidelberg, Mannheim, Darmstadt and Ludwigshafen. It is the most prominent and concentrated biotech cluster in Germany in the fields of personalized medicine and cancer research.

 

Technologiepark Heidelberg

Heidelberg Technology Park is a science park where major research institutes and global corporations work side by side. The synergies are manifold so that what emerges is a science-based society in which science finds scope for experimentation in industry and scientific research gains new perspectives as a result of international cooperation.

 

BioLAGO e.V.

BioLAGO is the cross-border health network for life sciences in the four-country-region of Lake Constance (Germany, Switzerland, Austria and Liechtenstein). The network links industry with science for innovations; it promotes knowledge transfer and the foundation of new firms.

 

Network Lab-on-a-Chip Technologies

Lab-on-a-Chip approaches (short: LoaC) are the combination and integration of several analytical steps of classical and new laboratory analysis on a glass, silicium or plastic chip. The goal is to achiev a high degree of automation as well as the parallelization of many analytical steps (keyword " High Content Screening").

The network focuses on innovative products, production processes and services primarily in the fields of

  • Point-of-care diagnostics systems / Biomarker development
  • Replacement of animal experiments by "organ-on-a-chip" approaches
  • cell analysis / microbiology
  • chip manufacturing

 

Brochure

Click on the image below to download our company brochure with information on Sciomics GmbH, antibody microarrays and potential applications of this technology.

 

About us

Antibody microarray with spots lined up in antibody form 

Sciomics – Antibody meets microarray

Sciomics GmbH was founded in the spring of 2013 as a spin-off company of the German Cancer Research Center (DKFZ) by Dr. Christoph Schröder and Dr. Jörg Hoheisel. Since 2003, our team has gained experience with production and application of antibody microarrays as a tool for analysing complex protein samples. With this background, Sciomics is able to offer complete analysis of your samples with standardised as well as customised arrays.

 

Analyse your protein sets of interest

Antibody microarrays make it possible to analyse complete signalling pathways, up- or downstream elements of your protein of interest or hits from next generation sequencing for their impact on protein level. Such an analysis requires only very small sample volumes, as little as 15µL of blood plasma, for example. This facilitates a robust and multiplex analysis of plasma or tissue proteins not only from human but also from small experimental animals such as the murine samples. We offer standardised arrays or produce customised arrays for your list of targets or with your selection of antibodies.

Based on more than a decade of experience in profiling studies with antibody microarrays, we also offer a complete analysis service including protein extraction from plasma, serum, tissue or cell culture samples, sample labelling and incubation as well as the subsequent data analysis.

 

Identification of protein biomarker signaturesTypical results for a highly parallel protein analyses with antibody microarrays

In addition to their application for profiling studies, antibody microarrays are a valuable tool for the identification or verification of potential protein biomarkers. Based on analyses using complex antibody microarrays, biomarker signatures were identified for a prognosis in bladder cancer and a diagnosis of pancreatic cancer. These are currently being validated in larger scale studies.

Contact us to learn more about the potential of complex antibody microarrays for your protein biomarker screening or verification study.

 

Scientific articles

Please find below selected scientific articles on the antibody microarray platform or its application in biomedical studies for a protein profiling published in peer-reviewed journals. The articles were either published by our customers or by the founders and employees of Sciomics.

 

Scientific articles by our customers and partners

 

 

 

Selected scientific articles by our founders and employees

 

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